M11461 is normally associated with Hg A
However it was found in a R-L371 testee.
Population Geneticists say: " Given that the individual is hg R, it sounds highly likely that the SNP is a homoplasy (i.e., a recurrent mutation).
This interpretation is further bolstered by the fact that the coordinate in question is a CpG site. That is, 17971872 is a G, which means that the C is often methylated. When a methylated C becomes deaminated, it is a T. Consequently, this is the most common type of mutation, and therefore most inclined to recurrence."
Rating:
[5 of 5 Stars!]