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M11461
[M11461]

M11461

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Date Added: Tuesday 03 June, 2014

by George Jones

M11461 is normally associated with Hg A

However it was found in a R-L371 testee.

Population Geneticists say: " Given that the individual is hg R, it sounds highly likely that the SNP is a homoplasy (i.e., a recurrent mutation).
This interpretation is further bolstered by the fact that the coordinate in question is a CpG site. That is, 17971872 is a G, which means that the C is often methylated. When a methylated C becomes deaminated, it is a T. Consequently, this is the most common type of mutation, and therefore most inclined to recurrence."

Rating: 5 of 5 Stars! [5 of 5 Stars!]

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